Publication List
Selected Publications (past five years)
1. Tsai-Chun Chung, Chu-Chun Liang, Min-Wei Huang, Tianle Chen, Yi-Chen Ethan Li, I-Chi Lee*, and Po-Yen Chen*. Machine Learning Driven Design of Nerve-on-A-Chip Platforms for Promoting and Directing Neurite Outgrowth. Advanced functional materials. 2025. 2506074. Doi: https://doi.org/10.1002/adfm.202506074 (通訊作者/國際合作 (SCI, IF:18.5, Chemistry multidisciplnary 10/231=4.32%)
2. Yu-Chun Yeh, Pin-Yuan Chen, Ko-Ting Chen* and I-Chi Lee*. Innovative MXene/SilMA-Based Conductive Bioink for ThreeDimensional Bioprinting of Neural Stem Cell Spheroids in Neural Tissue Engineering. ACS Applied Materials & Interfaces. 2025, 17, 10402-10416. (SCI, IF: 8.5 Materials science, multidisciplinary 68/439=15%)
3. Chu-Chun Liang, Po-Yen Chen, Nien-Che Liu, and I-Chi Lee*. Comparison between dynamic versus static models and real-time monitoring of neuronal dysfunction in Alzheimer disease on chip platform. Lab on a chip. 2024. 24, 1887-1902 (通訊作者/國際合作 Journal back cover). (SCI, IF:6.1, Biomedical research methods 7/77=9%)
4. I-Chi Lee*, Yi-Chen Ethan Li*, James L. Thomas, Mei-Hwa Lee*, and Hung-Yin Lin*. Recent Advances Using MXenes in Biomedical Applications. Materials Horizons. 2024, 11(4), 876-902. Journal cover (SCI, IF: 13.3 Materials science, multidisciplinary 29/344=8.4%) (第一/通訊)
5. Hao-Wei Lee; Ko-Ting Chen; Yi-Chen Ethan Li; Chao-Ying Chiang; Yu-Chun Yeh; I-Chi Lee*. Dual Crosslinking Silk Fibroin-based bioink development and the application on neural stem/progenitor cells spheroid laden 3D bioprinting. 2024. 269, 131720. International Journal of Biological Macromolecules. 2024 (通訊作者) (SCI, IF: 8.2, polymer science, 5/86=5.8%) (通訊作者)
6. Wu-Xun Chen, Nai-Chen Cheng, Yan-Jun Chen, and I-Chi Lee*. Characterization of silk fibroin-based microneedles and in vitro study of stromal cell-derived factor-1-loaded microneedles on adipose stem cell recruitment. International Journal of Biological Macromolecules. 2023, 233, 123537 (通訊作者) (SCI, IF: 8.2, polymer science, 5/86=5.8%)
7. Siaka Fadera, Pin-Yuan Chen, Hao-Li Liu#, and I-Chi Lee* Induction Therapy of Retinoic acid with a TMZ-loaded Gold Nanoparticle-Associated Ultrasound Effect on Glioblastoma Cancer Stem-like Colonies. ACS applied materials and interfaces. 2021.13(28), 32845-32855 (SCI, IF: 9.5 Materials science, multidisciplinary 55/344) (通訊作者)
Other Publications
2025
1. Tsai-Chun Chung, Chu-Chun Liang, Min-Wei Huang, Tianle Chen, Yi-Chen Ethan Li, I-Chi Lee*, and Po-Yen Chen*. Machine Learning Driven Design of Nerve-on-A-Chip Platforms for Promoting and Directing Neurite Outgrowth. Advanced functional materials. 2025. 2506074. Doi: https://doi.org/10.1002/adfm.202506074 (通訊作者/國際合作 (SCI, IF:18.5, Chemistry multidisciplnary 10/231=4.32%)
2. Yu-Chun Yeh, Pin-Yuan Chen, Ko-Ting Chen,* and I-Chi Lee*. Innovative MXene/SilMA-Based Conductive Bioink for Three Dimensional Bioprinting of Neural Stem Cell Spheroids in NeuralTissue Engineering. ACS Applied Materials & Interfaces. 2025, 17, 10402-10416. (SCI, IF: 8.5 Materials science, multidisciplinary 68/439=15%) (NSTC113-2640-B-007-001-and NSTC 112-2221-E-007-012-MY3, National Tsing Hua University (grants 111F7MDUE1 and112F7MCWE1), and Chang Gung Memorial Hospital (grantsCORPG3M0031 and CORPG3N0041)
3. Hoi Man Iao, Chih-Ying Chen, Ya-Hui Lin, Wan-Chi Pan, Chun-Yi Liang, Hsiu-Ching Liu, Lo-Jei Ching, Pei-Yu Weng, Min-Ren Chiang, Ru-Siou Hsu, Tsu-Chin Chou, I-Chi Lee, Lun-De Liao, Li-An Chu*, Shih-Hwa Chiou*, Shang-Hsiu Hu*. Wireless in situ catalytic electron signaling-mediated transcriptomic reprogramming for neuron regeneration via adaptable antennas. Advanced Science. 2025, 2504786 (SCI, IF=14.3, Materials science, multidisciplinary 29/439=6.6%).
4. Wan‐Chi Pan, Ya‐Hui Lin, Hoi Man Iao, Yun‐Hsuan Chang, Yin‐Hsu Chen, Hsiu‐Ching Liu, Ngoc‐Tri Tran, I‐Chi Lee, Hui‐Wen Lien, Eric Hwang, Li‐An Chu, and Shang‐Hsiu Hu. In Situ Magnetoelectric Generation of miRNA Sponges and Wireless Electric Stimulus by Conductive Granular Scaffolds for Nerve Regeneration. Advanced Materials. 2025, (SCI, IF=26.8, Chemistry multidisciplinary 3/241=1.2%).
5. Shuaiming He, Tianle Chen, Zhulin Li, Yang Li, Joshua M. Little, Chu-Chun Liang, Yiqiang Wu, I-Chi Lee, Po-Yen Chen. Lightweight, Strong, Bendable, and Biodegradable Straws Enabled by Nano-and Microarchitecture Tuning of the Cell Wall and a Molecular Welding Strategy. Advanced Sustainable Systems. 2025. 2400737. (國際合作)
2024
1. Chu-Chun Liang, Po-Yen Chen, Nien-Che Liu, and I-Chi Lee*. Comparison between dynamic versus static models and real-time monitoring of neuronal dysfunction in Alzheimer disease on chip platform. Lab on a chip. 2024. 24, 1887-1902 (通訊作者/國際合作 Back cover). (SCI, IF:6.1, Biomedical research methods 7/77=9%) (MOST 110-2124-M-005 -001 -MY3 and MOST107-2314-B-182- 017-MY3)
2. Tianle Chen, Shuaiming He, Zhenqian Pang, Yang Li, Snehi Shrestha, Joshua M. Little, Haochen Yang, Jiayue Sun, I-Chi Lee, Taylor J. Woehl, Teng Li*, Liangbing Hu*, and Po-Yen Chen*. Machine Intelligence-Accelerated Discovery of All-Natural Plastic Substitutes. Nature Nanotechnology 2024. 19, 782–791 (SCI, IF=38.3, Materials science, multidisciplinary 5/342=1.4%) (國際合作)
3. Hao-Wei Lee; Ko-Ting Chen; Yi-Chen Ethan Li; Chao-Ying Chiang; Yu-Chun Yeh; I-Chi Lee*. Dual Crosslinking Silk Fibroin-based bioink development and the application on neural stem/progenitor cells spheroid laden 3D bioprinting. International Journal of Biological Macromolecules. 2024. 269, 131720. (通訊作者) (SCI, IF: 8.2, polymer science, 5/86=5.8%) (MOST 110-2314-B-007-001-MY3 and MOST 110-2314-B-007-001-MY3, 111F7MDUE1, CORPG3M0031)
2023
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Wu-Xun Chen, Nai-Chen Cheng, Yan-Jun Chen, and I-Chi Lee*. Characterization of silk fibroin-based microneedles and in vitro study of stromal cell-derived factor-1-loaded microneedles on adipose stem cell recruitment. International Journal of Biological Macromolecules. 2023, 233, 123537 (通訊作者) (SCI, IF: 8.2, polymer science, 5/86=5.8%) (MOST 108-2314-B-182-004 and MOST107-2314-B-182-017-MY3)
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I-Chi Lee*, Yi-Chen Ethan Li*, James L. Thomas, Mei-Hwa Lee*, and Hung-Yin Lin*. Recent Advances Using MXenes in Biomedical Applications. Materials Horizons. 2024,11,876 (SCI, IF: 13.3 Materials science, multidisciplinary 29/344=8.4%) (第一/通訊)(Journal cover)
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Han-Wen Yang, Nien-Tzu Yeh, Tzu-Ching Chen, Yu-Chun Yeh, I-Chi Lee*, Yi-Chen Ethan Li*. A Printable Magnetic-responsive Iron Oxide Nanoparticle (ION)-laden Gelatin methacryloyl (GelMA) Ink For Soft Bioactuator/Robots Applications. Polymers. 2024. 16(1), 25-45. (2023 Dec. online) (SCI, IF:5, Polymer science, 16/86=18.6%) (通訊作者)
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Yi-Chieh Chan, Ya-Hui Lin, Hsiu-Ching Liu, Ru -Siou Hsu, Ming-Ren Chiang, Li-Wen Wang, Tsu-Chin Chou, Tsai-Te Lu, I-Chi Lee, Li-An Chu*, and Shang-Hsiu Hu*. In situ magnetoelectric generation of nitric oxide and electric stimulus for nerve therapy by wireless chargeable molybdenum carbide octahedrons. Nano today. 2023, 51.101935 (SCI, IF: 17.4 Materials science, multidisciplinary 19/342=5.6%)
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Tsai-Chun Chung, Ya-Hsin Hsu, Tianle Chen, Yang Li, I-Chi Lee, Ping-Shan Lai, Yi-Chen Li, and Po-Yen Chen. Machine Learning Integrated Workflow for Predicting Schwann Cell Viability on Conductive MXene Biointerfaces. ACS Applied Materials & Interfaces. 2023, 15(39), 46460-46469 (SCI, IF: 9.5 Materials science, multidisciplinary 55/344) (國際合作)
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Min-Ren Chiang, Ya-Hui Lin, Wei-Jie Zhao, Hsiu-Ching Liu, Ru-Siou Hsu, Tsu-Chin Chou, Tsai-Te Lu, I-Chi Lee, Lun-De Liao, Shih-Hwa Chiou, Li-An Chu,* and Shang-Hsiu Hu*. In Situ Forming of Nitric Oxide and Electric Stimulus for Nerve Therapy by Wireless Chargeable Gold Yarn-Dynamos. Advanced Science. 2023. 2303566. (online publish) (SCI, IF: 15.1 Materials science, multidisciplinary 24/344)
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Hsiu-Ching Liu, Chu-Han Huang, Min-Ren Chiang, Ru-Siou Hsu, Tsu-Chin Chou, Tsai-Te Lu, I-Chi Lee, Lun-De Liao, Shih-Hwa Chiou, Zhong-Hong Lin, Shang-Hsiu Hu*. Sustained Release of Nitric Oxide-Mediated Angiogenesis and Nerve Repair by Mussel-Inspired Adaptable Microreservoirs for Brain Traumatic Injury Therapy. Advanced Healthcare Materials. 2023, 2302315. (online publish) (SCI, IF: 10 Engineering, biomedical 8/96=8.3%)
2022
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Ru-Siou Hsu, Ssu-Ju Li, Jen-Hung Fang, I-Chi Lee, Li-An Chu, Yu-Chun Lo, Yu-Jen Lu, You-Yin Chen, and Shang-Hsiu Hu. Wireless Charging-Mediated Angiogenesis and Nerve Repair by Adaptable Microporous Hydrogels from Conductive Building Blocks. Nature communications. 2022. (SCI, IF: 17.694, Multidisciplinary sciences, 5/134)
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I-Chi Lee*, Yu-Chieh Lin, Hao-Li Liu, and Nien-Che Liu. Dual-Frequency Ultrasound Enhances Functional Neuron Differentiation from Neural Stem Cells by Modulating Ca2+ Dynamics and the ERK1/2 Signaling Pathway. 2022. Journal of Cellular Physiology. 2022, 1-14 (6.513, physiology, 10/81) (第一作者/通訊作者)
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Nien-Che Liu, Chu-Chun Liang, Yi-Chen Ethan Li and I-Chi Lee*. A Real-Time Sensing System for Monitoring Neural Network Degeneration in an Alzheimer’s Disease-on-a-Chip Model. Pharmaceutics. 2022. 14(5), 1022 (6.321, pharmacology &pharmacy 29/276) (通訊作者)
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Trong Ming Don, Michelle Chen, I-Chi Lee, and Yi-Cheng Huang*. Preparation and characterization of fast dissolving ulvan microneedles for transdermal drug delivery system. International Journal of Biological Macromolecules. 2022, 207, 15 (SCI, IF: 8.025, Chemistry, applied, 8/72)
2021
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Siaka Fadera, Pin-Yuan Chen, Hao-Li Liu#, and I-Chi Lee* Induction Therapy of Retinoic acid with a TMZ-loaded Gold Nanoparticle-Associated Ultrasound Effect on Glioblastoma Cancer Stem-like Colonies. ACS applied materials and interfaces. 2021.13(28), 32845-32855 (SCI, IF: 10.383 Materials science, multidisciplinary 49/345) (通訊作者)
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Xuemei Fu, Haitao Yang, Zhipeng Li, Nien-Che Liu, Pei-Shan Lee, Kerui Li, Shuo Li, Meng Ding, John S. Ho, Yi-Chen Ethan Li*, I-Chi Lee*, and Po-Yen Chen*. Cation-Induced Assembly of Conductive MXene Fibers for Wearable Heater, Wireless Communication, and Stem Cell Differentiation. ACS Biomaterials Science & Engineering. 2021 (SCI, IF: 5.395 Materials Science, biomaterials, 18/44) . (通訊作者/國際合作)
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Ruey-Shin Juang, Xing Su and I-Chi Lee*. Feasibility Assessment of Parathyroid Hormone Adsorption by Using Polysaccharide Based Multilayer Film Systems. 2021, 13, 2070. (SCI, IF:4.967, Polymer science, 16/90)(通訊作者)
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Pei-Ju Tsai, I-Chi Lee (equal contribution), Meng-Hua Yen, Yi-Chen Ethan Li*. Development and Customization of a Concentration Gradient Microgenerator by Extrusion 3D Printing for Drug Testing in Laboratory Studies. 2021, 23, e00160. Bioprinting. (共一作者)
2020
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S Fadera, N-C Cheng, T-H Young, and I-C Lee*. In vitro study of SDF-1α-loaded injectable and thermally responsive hydrogels for adipose stem cell therapy by SDF-1/CXCR4-axis. Journal of Materials Chemistry B. 2020, 8, 10360. (SCI, IF:7.571, Materials science, Biomaterials, 10/44)(通訊作者)
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Yi-Chen Li* and I-Chi Lee*. The Current Trends of Biosensors in Tissue Engineering. Biosensors. 2020, 10, 88 (SCI, IF:5.743, instruments & intrumentation, 8/64 )(通訊作者)
2019
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I-Chi Lee*, Siaka Fadera, and Hao-Li Liu#. Strategy of Differentiation Therapy: Effect of Dual Frequency Ultrasound on the Induction of Liver Cancer Stem-like Cells. Journal of Materials Chemistry B. 2019, 7, .5401-5411 (SCI, IF:6.331, Materials science, Biomaterials, 9/38)
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I-Chi Lee*. Cancer-on-a-chip for drug screening. Current Pharmaceutical Design. 2019 24(45), 5407-5418 (SCI, IF:2.412, Pharmacology & Pharmacy, 148/267).
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I-Chi Lee*, Hui-Ju Wu, and Hao-Li Liu#. Dual-frequency ultrasound induces neural stem/progenitor cell differentiation and growth factor utilization by enhancing stable cavitation. ACS Chemical Neuroscience. 2019.10(3) 1452-1461 (SCI, IF:4.486 Chemistry, Medical 13/61).
2018
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I-Chi Lee*, Yu-Chieh Wu, and Wei-Shan Hung. Hyaluronic acid-based multilayer films regulate hypoxic multicellular aggregation of pancreatic cancer cells with distinct cancer stem cell-like properties. ACS applied materials and interfaces. 2018, 10, 38769-38779 (SCI, IF: 9.229 Materials science, multidiscipinary 33/314) (第一作者兼通訊)
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Liu YC, Lee IC* (equal contribution), Lei KF#. Towards the Development of an Artificial Brain on a Micropatterned and Material-regulated Biochip by Guiding and Promoting the Differentiation and Neurite Outgrowth of Neural Stem/Progenitor Cells. ACS applied materials and interfaces. 2018, 10(6), 5269-5277. (SCI, IF: 9.229 Materials science, multidiscipinary 33/314) (共同第一作者兼通訊)
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Lee IC*, Chang JF and Juang RS#. Recent advances and perspectives on capture and concentration of label-free rare cells for biomedical science and engineering research. Journal of the Taiwan Institute of Chemical Engineers. 2018, 85, 40-55. (SCI, IF: 4.794, Engineering, Chemical 24/137)
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Liu YC, Lee IC* (equal contribution), Chen PY#. Biomimetic Brain Tumor Niche Regulates Glioblastoma Cells Towards a Cancer Stem Cell Phenotype. Journal of Neuro-Oncology. 2018, 137(3), 511-522. (SCI, IF: 3.060 CLINICAL NEUROLOGY 78/197)
2017
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Lee IC, Wu YC, Tsai SW, Chen CH, Wu MH*. "Fabrication of Two-layer Dissolving Polyvinylpyrrolidone Microneedles with Different Molecular Weights for in Vivo Insulin Transdermal Delivery," RSC Advances. 2017, 7, 5067-5075. (SCI, IF:3.289, Chemistry, multidiscipinary 49/193) (第一作者)
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Lee IC*, Lin WM, Shu JC, Tsai SW, Chen CH, and Tsai MT#. Formulation of two-layer dissolving polymeric microneedle patches for insulin transdermal delivery in diabetic mice. Journal of Biomedical Materials Research Part A. 2017, 105(1), 84-93 (SCI, IF: 3.231, Engineering Biomedical 19/78) (第一作者兼通訊)
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Lee MT, Lee IC, Tsai SW, Chen CH, Wu MH and Juang YJ*. Spin coating of polymer solution on polydimethylsiloxane mold for fabrication of microneedle patch. Journal of the Taiwan Institute of Chemical Engineers. 2017, 70, 42-48 (SCI, IF:4.217, Engineering, Chemical 19/134)
2016
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Lin YH*, Lee IC (equal first), Hsu WC, Hsu CH, Chang KP, Gao SS. Rapid fabrication method of a microneedle mold with controllable needle height and width. Biomedical microdevices. 2016. 18(5)85. (SCI, IF: 2.227 Engineering Biomedical 28/76) (共同第一作者)
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Tsai MT, Lee IC*, Lee ZF, Liu HL, Wang CC, Choia YC, Chou HY, and Lee JD. In vivo investigation of temporal effects and drug delivery induced by transdermal microneedles with optical coherence tomography. Biomedical optics express. 2016, 7(5), 1865-1876 (SCI, IF: 3.482, Optics 15/94) (通訊作者)
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Yi-Je Juang*, Yu Luen Deng, and I-Chi Lee. Membrane filtration: An unconventional route for fabrication of the flexible and dissolvable, polymer microneedle patches. Biomicrofluidics. 2016, 10, 044108. (SCI, IF: 2.708, Physics, fluids & plasmas 6/30)
2015
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Lee IC*, Chuang CC, and Wu YC. Niche Mimicking for Selection and Enrichment of Liver Cancer Stem Cells by Hyaluronic Acid-Based Multilayer Films. ACS applied materials and interfaces. 2015, 7 (40), 22188–22195 (SCI, IF: 9.229 Materials science, multidiscipinary 33/314) (第一作者兼通訊)
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Ko PT, Lee IC, MC Chen, SW Tsai*. Polymer microneedles fabricated from PCL and PCL/PEG blends for transdermal delivery of hydrophilic compounds. Journal of the Taiwan Institute of Chemical Engineers. 2015, 51, 1-8. (SCI, IF: 4.217, Engineering, Chemical 19/134)
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Lee IC*, and Chang JF. Label-free Selection and Enrichment of Cancer Stem Cells by Layer by Layer Build-Up Polyelectrolyte Multilayer films. Colloids and Surfaces B: Biointerfaces 2015, 125, 120-126 (SCI, IF: 3.997, Biophysics 13/72)
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Lee IC*, Wu YC, Cheng EM, and Yang WT. Biomimetic niche for neural stem cell differentiation using PLL/HA multilayer films. Journal of biomaterials application 2015, 29(10), 1418-1427 (SCI, IF: 2.764, Engineering, Biomedical, Rank: 29/76)
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Lee IC*, He JS, Lin KC, and Tsai MT*. Fabrication of a novel partial dissolving polymer microneedle patch for transdermal drug delivery. Journal of Materials Chemistry B. 2015, 3(2), 276-285 (SCI, IF:5.344, Materials science, Biomaterials, 9/38)
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Tao FF, Xiao X, Lei KF,* and Lee IC, Paper-based Cell Culture Microfluidic System. BioChip Journal. 2015, 9(2):97-104. (SCI, IF: 1.050, 70/78: Biochemical research methods)
2014
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Lee IC*, and Wu YC. Assembly of polyelectrolyte multilayer films on supported lipid bilayers to induce neural stem/progenitor cell differentiation into functional neurons. ACS applied materials and interfaces 2014, 6(16), 14439–14450 (SCI, IF: 9.229 Materials science, multidiscipinary 33/314) (第一作者兼通訊)
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Lee IC, Tsai HA, Liu YC, Shen CN and Chang YC*. Promoting Selection and Maintenance of Fetal Liver Stem/ Progenitor Cell Colonies by Supported Lipid Bilayer Based Materials. ACS applied and materials interfaces. 2014, 6(23), 20654-20663 (SCI, IF: 8.758 Materials science, multidiscipinary 33/314)
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Lei KF*, Lee IC* (eaqul contribution), Liu YC, and Wu YC. Successful Differentiation of Neural Stem/Progenitor Cells Cultured on Electrically Adjustable Indium Tin Oxide (ITO) Surface. Langmuir 2014 30, 14241-14249 (SCI, IF: 3.789, Materials science, multidiscipinary 61/284)
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Lee IC*, and Wu YC. Facilitating the neural stem/ progenitor cell Niche for Neural Lineage Differentiation by polyelectrolyte multilayer films. Colloids and Surfaces B: Biointerfaces 2014, 121 54-65 (SCI, IF: 3.997, Biophysics 13/72)
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Lee IC*, Lo TL, Young TH, Li YC, Chen, Nelson G, Chen CH and Chang YC*. Differentiation of Neural Stem/Progenitor Cells by Low Intensity Ultrasound. Ultrasound in Medicine and Biology. 2014, 40(9) 2195-2206 (SCI, IF: 2.645, Rank: 7/31)
Book and Book Chapter
Kin Fong Lei, I-Chi Lee, Tim C. Lei. Microfluidic Systems with Functional Patterned Surface for Biomedical Applications, Design of Polymeric Platforms for Selective Biorecognition. Chapter 11, P305-324.
Kin Fong Lei, I-Chi Lee and Yi-Chen Li. Advances in Drug Testing and Drug Delivery Systems. Nova Science Publishers.
Invited speaker and Chair (past five years)
Invited speaker. I-Chi Lee*, Nien-Che Liu and Chu-Chun Liang. Material based regulation of neural stem cells and the application of brain on a chip. International Conference on Precision Nanomedicine in Theranostics & the 2022 Annual Meeting of Taiwan Nanomedicine Society. (2022, July, 22-23)
Chair. 2022 台灣生醫材料與生物感測器應用技術研討會
Keynote speaker. I-Chi Lee*. Material based regulation of neural stem cells and the application of brain on a chip. Annual Meeting of Taiwanese Society of Biomedical Engineering (TSBME) 2021. (2021, Nov, 19-20)
Invited speaker. I-Chi Lee*. Chu-Chun Liang. Toward the development of brain on a chip and its application as an Alzheimer's disease model. BCRS 2021. (2021, Dec, 4)
Invited speaker. I-Chi Lee*. Fadera Siaka. “Regulation of cancer stem cell cells using polyelectrolyte multilayer nano-film system”. 2019 IEEE NANOMED. (2019, Nov, 21-24)
Invited speaker. I-Chi Lee*, Yu-Chieh Wu. “Niche Mimicking for Induction of Neural Stem/Progenitor Cells by Multilayer Films Based System”, Annual Congress of Tissue Engineering and Regenerative Medicine International Society Asian-Pacific 2016 (TERMIS-AP). (2016, Sep. 3-9)
SYIS評選Chair. Annual Congress of Tissue Engineering and Regenerative Medicine International Society Asian-Pacific 2016 (TERMIS-AP). (2016, Sep. 3-9)
Invited speaker. I-Chi Lee*. “Induction of Functional Neurons and Formation of Neural Network by Multilayer Films Based System”. International Symposium of Biotechnology on Biomaterials, Stem cells and Tissue Engineering (2017 ISBBST). (2017, Aug. 20-22)
Invited speaker. I-Chi Lee*. Yung Chiang Liu. “Formation of a Neural Network on a PEM based micropatterned platform”. 2017 IEEE NANOMED. (2017, Dec, 1-4)
Conferences (past five years)
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I-Chi Lee* , I-Sheng Yu. 3D Bioprinting Glioblastoma Spheroids: Silk Fibroin/HA Bioinks Mimic Matrix Stiffness Effects on Tumor Invasiveness and Macrophage Polarization. 2025 Termis-EU (2025, May. 19-23).
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Han-Wen, Yang, Chu-Chun Liang and I-Chi Lee* Development and Application of Brain-on-a-Chip for Parkinson's Disease modelling. 2024 BCRS & IADDS (2024, Aug. 15-16). (Poster award)
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Chih-Yu Wu, Chia-Wen (Kevin) Wu, Pornnapat Tungtrakarnkul, I-Chi Lee* Controlled Nitric Oxide Release via Ceria MOF-Loaded Microneedle Patch to Induce Immunogenic Cell Death in Cancer Therapy. 2024 BCRS & IADDS (2024, Aug. 15-16)
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Zi-Han Chen, Hung-Yin Lin, Mei-Hwa Lee, I-Chi Lee,* Development of Nanoparticle Loaded Microneedle Mediated Gene Delivery on the Application of Cancer Treatment. 2024 BCRS & IADDS (2024, Aug. 15-16). (Poster award)
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Wu-Xun Chen, I-Chi Lee* A three-in-one injectable hydrogel for reprogramming the immunosuppressive tumor microenvironment on triple-negative breast cancer therapy. 2024 BCRS & IADDS (2024, Aug. 15-16). (Poster award)
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Yu-Chun Yeh, I-Chi Lee ,* 3D bioprinting electrically conductive bioink on the application of neural Tissue Engineering. 2024 BCRS & IADDS (2024, Aug. 15-16). (Poster award)
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Li-Ying Peng, I-Chi Lee,* Preparation and Application of Double-Crosslinked High-Strength Hydrogels in Vascular Organ Chips: Establishment and Investigation of Atherosclerosis Models. 2024 BCRS & IADDS. (2024, Aug. 15-16)
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Ting-Wei Chang and I-Chi Lee*. Development of bioinks for 3D bioprinting in breast cancer metastasis chip. 2023 IEEE NANOMED (2023, Dec. 5- Dec. 8), Okinawa, Japan
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Chu-Chun Liang, and I-Chi Lee* .Fabrication and application of Amyloid-β induced neurotoxic model on brain chip for modeling dynamic versus static brain microenvironment. 2023 IEEE NANOMED (2023, Dec. 5- Dec. 8), Okinawa, Japan
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Ting-Wei Chang and I-Chi Lee*. Development of bioinks for 3D bioprinting of breast cancer microenvironment modeling. ISOMRM & BCRS. (2023, Aug. 31-Sep. 3)
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Zi-Han Chen, Hung-Yin Lin, Mei-Hwa Lee, and I-Chi Lee*. Development of Nanoparticle Loaded Microneedle Mediated Gene Delivery on the Application of Cancer Treatment. ISOMRM & BCRS. (2023, Aug. 31-Sep. 3) (Poster award)
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Wu-Xun Chen and I-Chi Lee*. A three-in-one injectable hydrogel for reprogramming the immunosuppressive tumor microenvironment on triple-negative breast cancer therapy. ISOMRM & BCRS. (2023, Aug. 31-Sep. 3) (Poster award)
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Li-Ying Peng and I-Chi Lee*. Vessel on a Chip with Hydrogel Based 3D Bioprinting Vessel-Like Construct. ISOMRM & BCRS. (2023, Aug. 31-Sep. 3)
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Yu-Chun Yeh and I-Chi Lee*. 3D bioprinting electrically conductive bioink on the application of neural Tissue Engineering. ISOMRM & BCRS. (2023, Aug. 31-Sep. 3)
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Chin-Yun Ting, and I-Chi Lee*, Preparation and evaluation of the synergistic effect of chemo-photothermal therpy by 2D material loaded GelMA microsphere. BCRS, 2022, Sep. 2 (佳作)
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Min-Wei Huang, I-Chi Lee* Neuron protective strategy in an in vitro model of glutamate-mediated neurotoxicity. BCRS, 2022, Sep. 2
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I-Sheng Yu, Hao-Wei Lee, and I-Chi Lee*. Development of Silk fibroin based bioinks and the application on 3D bioprinting. BCRS, 2022, Sep. 2
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Chu-Chun Liang, Kin-Fong Lee, and I-Chi Lee* Fabrication and Application of Neural Stem Cell Based Chip for Modeling Dynamic Brain Microenvironment. BCRS, 2021, Dec. 4. (佳作)
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Hao-Wei Lee, I-Chi Lee*. Preparation and characterization of 3D printable nature derived hydrogel on neural stem cells differentiation. BCRS, 2021, Dec. 4.
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I-Chi Lee*, Yu-Chieh Lin, and Hao-Li Liu. Ultrasound Effect and Mechanism on Neural Stem Cells Differentiation. TERMIS-AP, 2019, Oct14-17.
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I-Chi Lee *, Siaka Fadera, and Hao-Li Liu. Effect of Low Intensity Ultrasound on the Differentiation of Liver Cancer Stem-like Cells. SFB, 2019, April. 3-6
Research Grants (Active)
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國科會單一整合型專案計畫: 兒童癲癇性腦病變測試晶片開發與其在人工智慧專家系統輔助治療策略之應用-兒童癲癇性腦病變測試晶片開發與其在人工智慧專家系統輔助治療策略之應用(1/5): NSTC 113-2640-B-007-001- 年度計劃金額: 3,000,000
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轉移型黑色素細胞瘤的新療法策略開發-複合光熱誘導免疫原性細胞死亡介導免疫治療的雙層高分子微針貼片製備與應用(1/3): 112-2221-E-007 -012 -MY3 年度計劃金額: 1,300,000